Rick Santorum could end up revitalizing his campaign Tuesday evening if he's able to upset Mitt Romney in a trio of nominating contests in Minnesota, Missouri and Colorado.

First Read: A top campaign watchdog group is calling for a Justice Department criminal investigation into Super PACs supporting President Obama and GOP front runner Mitt Romney.

Texas is all but certain to have an even later say in choosing the Republican presidential nominee after what at first looked like a breakthrough deal over redistricting maps ended with wide rejection of the proposal.

A federal appeals court has declared California's Proposition 8 unconstitutional, paving the way for a likely U.S. Supreme Court showdown on the voter-approved law.

Science editor Alan Boyle's blog: What could be more wonderful than pictures of microscopic marvels? Brace yourself for some award-winning movies showing those marvels in action.

Psychiatrists say theyve identified some reasons why someone like Josh Powell would kill his sons and then himself.

Karen Handel, an executive with the Susan G. Komen for the Cure breast-cancer charity has resigned after a dispute over funding for Planned Parenthood.

Despite public health messages telling Americans to lower the amount of salt in their diets, 90 percent of people in the U.S. older than age 2 consume more than the recommended amount of sodium each day, a new report says.

NBC News speaks with Afghans around the country about the possibility of the Taliban's return to power.

Pennsylvania state prosecutors are asking that Jerry Sandusky's bail conditions to be tightened after receiving reports from local neighbors that the accused child molester has been spotted sitting on the deck of his house watching school children in a nearby playground.

Thousands of fans roared as New York Giants quarterback Eli Manning hoisted the team's Super Bowl trophy awarded to the National Football League champions, from a glittering blue-and-white float Tuesday during a victory parade through New York City, which Mayor Michael Bloomberg quipped should now be nicknamed the "Big Blue Apple."

Will there be a parade down New York City's Broadway for returning war veterans? Not quite yet, says the Pentagon, even though the idea is gathering steam.

Students at a Pennsylvania university can obtain the "morning-after" pill from an unusual source a vending machine at the campus health center.

Former President George W. Bush used a meeting of the nations auto dealers to defend his actions of bailing out Detroit, insisting he had no other choice but to completely sink the American economy.

Video feeds from some home users' Internet security cameras including children's rooms and bathroom scenes are being seen by others around the world because of a coding error that is part of the cameras' software.

Syrian forces continued their brutal assault in the city of Homs as Russias foreign minister held talks with President Bashar al-Assad in Damascus. ITNs Paul Davies reports(Nightly News)

Hoping to reverse the rising divorce rate among service members, organizations across the country are offering military couples and families places to have fun, bond and cope with life after wartime.

A Mexican drug cartel in the central mountainous state of Guanajuato has agreed to a 'Papal ceasefire' during an upcoming visit by Benedict XVI, a local newspaper reported on Tuesday.

As the world tips its collective hat to celebrate Charles Dickens 200th birthday it makes one wonder: Why do characters like Miss Havisham and Scrooge still resonate today?

If the Academy Awards hate the best song category so much, why don't they just dump it completely? First, only two songs were nominated, and now Deadline.com is reporting that neither will be performed at the ceremony.

Scientists say pythons are multiplying at an alarming rate in the Everglades, and now emergency workers in Florida are being trained to catch the powerful predators. WBBH-TV's Kim Brown reports.(NBC News)

Sears is struggling. Big department stores like Macys and J.C. Penney are treading water, while major apparel sellers like Gap and Talbots are losing market share and shrinking store counts.

Anyone who is surprised by the Obama campaign's announcement last night that it's encouraging Democratic donors to give money to the pro-Obama Super PAC wasn't paying attention in 2008.

We all know that meetings can be dull and boring. A new study shows that they can also make you stupid.

Republican presidential hopefuls have been campaigning in advance of contests Tuesday in Colorado, Minnesota and Missouri with a total of 70 delegates up for grabs. NBCs Peter Alexander reports.(TODAY)

After back-to-back fiascos in Nevada and Iowa, the term "caucus" may be on its way to becoming a bad word in the GOP lexicon.

Up to 10 million children are estimated to be working in Pakistan, according to UNICEF, as rising prices and a struggling economy force poor families to send them out to work.

Pakistanis reel in one of the biggest fish in the sea: a whale shark.

Florence Green, the world's last known veteran of World War I, has died at the age of 110, the care home where she lived said Tuesday.